Activating the healing power of silk in wound closure.

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From post-surgical wounds to simple lacerations
SYLKE® has you covered.

Every year, millions of patients suffer from complications due to reactions from wound closures and dressings made from synthetic meshes, paper tapes, and surgical adhesives.

At SYLKE® we’re developing need-based innovations to address these issues by combining decades of research with one of the most gentle, hypoallergenic materials on the planet.

SYLKE® truly is a "wound closure without compromise."

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SYLKE® Adhesive Wound Closure

“All-In-One” system provides wound closure strength AND wound dressing protection.

Silk Fibroin Technology

Created with 99.99% purified silk fibroin, a hypoallergenic bioprotein that enhances wound healing.

Flexible and Breathable

The mesh design contours over irregular and mobile wound surfaces and allows oxygen and exudate transfer to aid wound healing.

Offload Tension

Strong but gentle adhesive holds wound edges closed for 2 weeks to improve cosmetic outcomes.

Water Resistant

Two-week wear time through normal bathing routines.

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Try SYLKE® Adhesive Wound Closure

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The SYLKE® Difference

SYLKE® was designed with healing in mind, protecting the body’s first line of defense against infection, the skin. By combining one of the oldest biomaterials in wound healing with modern science and technology, SYLKE® looks to nature to promote complication free wound healing.


patients experience a medical adhesive related skin injury (MARSI) from the current standard of care in wound closures and dressings. MARSI can delay wound healing, cause scarring and increase the risk of infection.

The Secret is in the Silk

Learn more about the materials

SYLKE® is the only post-surgical wound closure made with silk fibroin, a naturally hypoallergenic material that is strong, flexible and clinically researched to aid in wound healing.

Silk Bioprotein as a Novel Surgical-Site Wound Dressing

A Prospective, Randomized, Single-Blinded, Superiority Clinical Trial

View on PubMed

Superiority of a Silk Surgical Site Wound Closure Device Over Synthetic Dressings

A Prospective, Randomized, Single-Blinded, Clinical Trial

View on PubMed

Easy to Apply & Remove

Applies in seconds and lasts for weeks. SYLKE® was invented by physicians to be used in the Hospital, ASC, doctor’s office, and at home.

View Instructions For Use (IFU)


Available for purchase “over the counter” right from our shop and shipped directly to you.

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