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2-Octyl Cyanoacrylate vs SYLKE
Every year, millions of patients suffer from painful complications due to reactions from wound closures and dressings made of synthetic compounds. These complications delay wound healing, cause additional scarring, and increase the risk of infection.
SYLKE® is the only post-surgical wound closure made with natural silk fibroin, a naturally non-immunogenic material that is strong, flexible, and clinically researched to aid in wound healing.
SYLKE® is the only post-surgical wound closure made with natural silk fibroin, a naturally non-immunogenic material that is strong, flexible, and clinically researched to aid in wound healing.
Discover a new standard of care.
SYLKE Adhesive Wound Closure is our groundbreaking solution, revolutionizing the management of incisions and lacerations. Crafted from 99.9% sericin-free, medical-grade silk fibroin, SYLKE provides a biocompatible, breathable, and water-resistant closure that gently yet securely adheres to the skin. Its innovative 360° stretch mimics the natural elasticity of skin, allowing for movement without compromising wound integrity. With up to 14 days of wear time, even on dynamic areas like joints, SYLKE is designed to protect the wound, offload tension, and support the body's natural healing process.
Non-Immunogenic
SYLKE® is crafted from 99.9% purified silk fibroin, making it biocompatible and gentle on sensitive skin. Unlike synthetic closures that can trigger allergic reactions, SYLKE® is free from irritants, ensuring a safer healing process for all patients.
Quick Application, Gentle Removal
SYLKE® applies instantly with no need for glue or drying time, unlike cyanoacrylate products, which require waiting for the adhesive to cure. Removal is gentle and painless, with no harsh solvents or skin stripping.
2-Week Wear Time
SYLKE® is designed to stay securely in place for a full 14 days, offering long-lasting protection and consistent wound support without the need for frequent dressing changes.
Water Resistant
SYLKE® provides reliable water resistance, allowing patients to shower normally during the healing process without losing adhesion. Its silk fibroin mesh is hydrophobic, meaning water beads up and flows off without affecting the adhesive.
Breathable
SYLKE®'s woven mesh is naturally breathable, allowing oxygen to promote healthy healing while reducing the risk of moisture buildup.
Offloads Tension
SYLKE® is engineered to evenly distribute tension across the wound, reducing the risk of blistering and dehiscence, while enhancing cosmetic outcomes, especially in high-movement areas like joints.
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SYLKE® Adhesive Wound Closure
Frequently Asked Questions
SYLKE® is made from 99.99% pure silk fibroin mesh with a biocompatible pressure-sensitive adhesive. The silk fibroin is naturally sourced and goes through a proprietary process to remove sericin, making it hypoallergenic and safe for sensitive skin.
SYLKE® has undergone extensive biocompatibility testing and is designed to be gentle on the skin, with no observed allergic reactions in clinical trials. The silk fibroin is hypoallergenic due to the removal of the sericin protein, and the adhesive is skin-friendly.
SYLKE® is indicated for use on clean, dry wounds, including simple lacerations, cuts, punctures, and post-surgical wounds. It should not be used on infected or actively bleeding wounds.
SYLKE® functions as both a wound closure by approximating skin edges and offloading tension to facilitate healing. Additionally, it acts as a dressing, forming a protective barrier that shields the wound from external contaminants.
No, SYLKE® does not require any glue like 2-octyl cyanoacrylate products. Its built-in, pressure-sensitive adhesive eliminates the need for messy glue application, significantly speeding up operating room time. SYLKE® can be applied in seconds and stays securely in place for up to 14 days. Removal is also much easier and gentler compared to 2-octyl products, which often require chemical solvents and can cause skin irritation or stripping.
No, SYLKE® is not intended to replace subcuticular or dermal sutures. Instead, it complements them by evenly distributing tension and preventing dead spaces, supporting the healing process.
SYLKE® is designed for up to 14 days of wear, including regular bathing. It provides robust protection throughout this period without requiring dressing changes.
Yes, SYLKE® is water-resistant, allowing patients to shower normally while it remains in place. However, full immersion in water, such as swimming or baths, is not recommended.
SYLKE® is semi-occlusive, meaning it allows breathability while still managing wound exudate. This supports an optimal healing environment by letting air in and keeping harmful contaminants out.
While silk fibroin has natural antimicrobial properties, SYLKE® itself is not classified as an antimicrobial dressing. It is designed to support healing by maintaining skin integrity without the need for antimicrobial agents.
Yes, SYLKE® is ideal for dynamic areas, such as knees and hips, because its 360° stretch mimics the natural movement of the skin.
SYLKE® can be easily trimmed to fit various wound lengths and shapes, making it highly versatile for different types of surgeries, specialties, and anatomical regions.
To remove SYLKE®, gently lift one edge and peel it off slowly along the line of the wound, using your other hand to stabilize the skin. Any residual adhesive can be cleaned off with warm soapy water or an alcohol pad.
If SYLKE® shows signs of strikethrough (fluid leakage through the dressing), it does not need to be replaced unless the wound becomes excessively saturated or soiled. A small amount of fluid or dried blood is normal and does not affect the dressing’s performance. If the dressing becomes fully saturated, it should be replaced.
Please email purchase orders to po@sylke.com, or order here online with a credit card.
Latest News
Read Our Blog
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San Diego Business Journal: SYLKE® Nets $5.5 in Physician-Led Fundraise
https://www.sdbj.com/life-sciences/medical-devices/sylke-nets-5-5m-in-physician-led-fundraise/ LA JOLLA – Sylke Inc., a biotech company that has pa...
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MedTech Dive: SYLKE® Presents Breakthrough in Post-Surgical Wound Healing and Secures $5.5 Million in Seed Funding
Company Shows 90 Percent Fewer Wound Healing Complications Compared to Industry Standards; Seed to Fuel New Innovations and Scaling
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Allure Best of Beauty 2024: Breakthrough Winners
https://www.allure.com/story/best-of-beauty-breakthrough-awards-winners-2024#Sylke-Adhesive-Wound-ClosureBest Breakthroughs: Sylke Adhesive W...
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Medical Design & Development: Hypoallergenic Silk Fibroin Surgical Dressing Could Reduce Complications
Hypoallergenic Silk Fibroin Surgical Dressing Could Reduce Complicationshttps://www.medicaldesigndevelopment.com/topics/surgical/news/22876828/hypo...