We are on a mission to change post-surgical wound healing forever.

- M. Mark Mofid, MD FACS

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“All-in-One” Wound Closure

At SYLKE®, we set out to make the world’s most natural, versatile, and gentle wound closure device that prioritizes patient care and comfort above all else. We designed SYLKE® for the post-operative care of surgical incisions, in emergency departments for laceration repair and at home for patient-applied wound management.

Wound coverage typically falls into two categories – closure devices and dressings. SYLKE® performs both of these very important roles simultaneously. SYLKE® is a wound closure device—holding the edges of a wound together while offloading tension through a 360° stretch silk fibroin mesh that mimics the elasticity of skin and allows the silk to move with you, decreasing the disruption of the delicate new matrix of cells. SYLKE® is also a dressing—the biocompatible, pressure-sensitive, breathable adhesive protects the wound from outside contaminants while allowing for the management of mild to moderate exudate.

SYLKE® is truly a closure device and a dressing “all-in-one”.

Let’s take a closer look at the importance of these functions. Closure devices hold the edges of a wound together to help promote wound healing. Removing space between the wound edges allows for growth cells to freely migrate across the injured surfaces and to begin building a foundation of new collagen cells. Topical wound closure devices help to minimize and redistribute skin tension which improves the quality of migrating cell repair. This helps to reduce scars and increases the rate of healing. Unfortunately, the closure devices available in most hospitals are either harsh chemical glues or weak and inelastic paper tapes. Instead of helping the wound to heal, these closure devices can irritate the skin and cause damage to the surrounding healthy tissue, resulting in issues like allergic reactions, redness and swelling. Furthermore, their stiff and inelastic nature can tear the skin during movement, creating even more injuries for your body to repair. Dressings cover the wounds to protect them from outside contaminants like bacteria and to absorb wound exudate. These dressings are often much larger than the incision and have difficulty staying adherent to the body for longer than a couple of days. Also, dressings don’t hold a wound closed; they only cover and protect.

SYLKE® Adhesive Wound Closure
Available as a sterile 2.5 cm by 32 cm strip, allowing use on a variety of wound lengths and for any excess to be trimmed away.

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Clinical Comparisons

In a prospective, randomized, single-blinded clinical trial conducted in collaboration with The Johns Hopkins School of Medicine and UC San Diego, a SYLKE® Prototype was compared to the current standard of care wound closures.

Medical adhesive related skin injuries (MARSI) and associated complications were primary and secondary end points.

Click here to read the first arm of the study published in the Aesthetic Surgery Journal Open Forum.

Preventing Allergic Contact Dermatitis

Description: Patient developed severe allergic contact dermatitis to a 2-cyanoacrylate adhesive with mesh dressing on the patient’s left side. The patient is a 29-year-old transgender male on postoperative day 4 status post reduction mammaplasty using the Passot technique. The patient’s right chest was closed and dressed with the SYLKE® prototype and remained unaffected.

1 sylke before after showing the prevention of allergic dermatitis.webp__PID:d722ce3f-30b9-4e82-bf49-0d0ba0bbb448
2 sylke before after showing decreased blistering.webp__PID:22ce3f30-b90e-42bf-890d-0ba0bbb44825

Decreased Blistering

Description: Patient developed a large fluid filled vesicle on their left side dressed with adhesive paper tape. The patient is a 70-year-old female day 4 status post mastopexy. The patient’s right breast was closed and dressed with the SYLKE® prototype and showed no signs of blistering.

Reduced Wound Dehiscence

Description: Patient presented with wound dehiscence at the triple point of the breast on the side dressed with 2-cyanoacrylate adhesive and mesh. The patient is a 41-year-old female on day 22 status post reduction mammoplasty. The side dressed with the SYLKE® prototype showed no signs of wound dehiscence.

3 sylke before after showing reduced wound dehiscence.webp__PID:ce3f30b9-0e82-4f49-8d0b-a0bbb4482540
4 sylke before after showing reduced wound dehiscence.webp__PID:3f30b90e-82bf-490d-8ba0-bbb44825402f

Reduced Wound Dehiscence

Description: Patient presented with wound dehiscence at the triple point of the breast on the side dressed with 2-cyanoacrylate adhesive and mesh. The patient is a 36-year-old female on day 14 status post reduction mammoplasty. The side dressed with the SYLKE® prototype showed no signs of wound dehiscence.

Improved Wound Healing

Description: On day 15 post reduction mammaplasty, a 26-year-old female patient presented with inflammation, erythema and pain at the triple point on the left breast dressed with adhesive tape. The patient’s right breast was closed and dressed with the SYLKE® prototype and showed no signs of wound healing complications.

5 sylke before after showing improved wound healing.webp__PID:30b90e82-bf49-4d0b-a0bb-b44825402f30
6 sylke before after showing improved wound healing.webp__PID:b90e82bf-490d-4ba0-bbb4-4825402f300b

Improved Wound Healing

Description: Photograph of a 51-year-old female patient 14 days post abdominoplasty. Erythema and skin discomfort were noted on the patient’s right side dressed with adhesive tape. The patient’s left abdomen was closed and dressed with the SYLKE® prototype, which showed no signs of wound healing complications.

Improved Scar Outcomes

Description: Photographs of a 56-year-old female patient 5 months post brachioplasty. In the top panel, the patient’s right arm was dressed with adhesive tape. The hypertrophic scar is wider, thicker, and displays more pronounced neovascular irregularities compared to bottom panel, where the patient’s left arm was dressed with the SYLKE® prototype.

7 sylke before after showing improved scar outcomes.webp__PID:0e82bf49-0d0b-40bb-b448-25402f300b44

Silk Bioprotein as a Novel Surgical-Site Wound Dressing

A Prospective, Randomized, Single-Blinded, Superiority Clinical Trial

View on PubMed

Superiority of a Silk Surgical Site Wound Closure Device Over Synthetic Dressings

A Prospective, Randomized, Single-Blinded, Clinical Trial

View on PubMed

Easy to Apply & Remove

Applies in seconds and lasts for weeks. SYLKE® was invented by physicians to be used in the Hospital, ASC, doctor’s office, and at home.

View Instructions For Use (IFU)

Shop SYLKE®

Available for purchase “over the counter” right from our shop and shipped directly to you.

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