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Redefining skin closure with silk fibroin.
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The Final Step, The First Impression
Application & Removal

SYLKE®
Application

SYLKE®
Removal
Why SYLKE?

🌱
Biocompatible
A natural structural protein, not a synthetic polymer. Silk fibroin derived from Bombyx mori, woven into a comfortable, breathable mesh that naturally conforms to tissue contour.

👋
Made Without Cyanoacrylates
Pressure-sensitive adhesive that bonds immediately on contact; simply press to secure. Not made with natural rubber latex. Contains no cyanoacrylate.

🩹
Simple
Pre-slit release liner with a 1.5" tab for controlled, sequential placement along the wound. Covers the adhesive surface until application.

💦
Water-Resistant
Water-resistant; avoid soaking or prolonged immersion.

💪
Holds Together Skin Edges
Designed to hold together well-approximated skin edges and protect the wound.

🗓️
Up to 2 Week Wear Time
Can be worn for up to two weeks.

🤝
Adjunct to Sutures or Staples
Indicated for topical closure and coverage of thoroughly cleansed simple lacerations and minor cuts, where it may be used as the primary skin closure. SYLKE® is also indicated for topical closure and coverage of post-surgical skin incisions in which deeper layers have been closed, where it is used as an adjunct to sutures or staples.
Sourced from India
SYLKE® begins its journey in India, the birthplace of Ayurvedic medicine. Here, we ethically harvest silk fibroin from family-tended mulberry groves, honoring centuries of healing heritage. Our process is certified Cradle to Cradle™—ensuring it is cruelty-free, pesticide-free, and fully biodegradable. By carefully removing the outer sericin layer, we reveal the pure fibroin core, a naturally occurring protein recognized for its strength and biocompatibility.
Woven in Italy
In Northern Italy, a region renowned for textile elegance, our raw silk is transformed by master craftsmen. Through a process of precise twisting and spooling, fibers are woven on advanced looms into a proprietary medical-grade mesh. This collaboration of tradition and technology creates a material that balances exceptional tensile strength with a delicate, breathable finish.
Assembled in USA
Advanced manufacturing brings SYLKE® to life in the United States. From lamination in New Hampshire to final conversion in Southern California, every step is executed under strict clean-room conditions. We apply medical-grade adhesive, slit to exact specifications, and subject every unit to rigorous seal testing. This ensures a sterile, flawless product that meets the highest standards of safety before it ever leaves our facility.
Shipped to You
Engineered for the demands of the modern operating room, SYLKE® Skin Closure delivers biocompatible skin closure. Order today with complimentary FedEx 2Day® shipping in the USA, just in time for your next case.
32cm, 24cm, or 16cm
3 Sizes Now Available










SYLKE® Skin Closure
SYL-WC-32-010
AAHKS Industry Innovation Award (2025)
Breakthrough Designation with Premier GPO (2025)
Allure Best of Beauty Awards: Breakthroughs (2024)
Ships within 1 business day.
2-Year Shelf Life
Free FedEx 2Day® Shipping
Request Free Sterile Samples
Product Specifications
Available box configurations.
| SKU | Description | Size/EA | Quantity | UOM | EA/BX |
|---|---|---|---|---|---|
| SYL-WC-32-010 | SYLKE® Skin Closure | 32cm x 2.5cm | 1 | BX | 10 |
| SYL-WC-32-050 | SYLKE® Skin Closure | 32cm x 2.5cm | 1 | BX | 50 |
| SYL-WC-24-010 | SYLKE® Skin Closure | 24cm x 3.4cm | 1 | BX | 10 |
| SYL-WC-24-050 | SYLKE® Skin Closure | 24cm x 3.4cm | 1 | BX | 50 |
| SYL-WC-16-010 | SYLKE® Skin Closure | 16cm x 2.5cm | 1 | BX | 10 |
| SYL-WC-16-050 | SYLKE® Skin Closure | 16cm x 2.5cm | 1 | BX | 50 |
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Latest Stories
SYLKE® Awarded Breakthrough Technology Designation with Premier, Inc.
Read moreabout SYLKE® Awarded Breakthrough Technology Designation with Premier, Inc.
SYLKE® Named an Allure 2024 Best of Beauty Breakthrough
Read moreabout SYLKE® Named an Allure 2024 Best of Beauty Breakthrough
SYLKE® Receives the 2025 AAHKS Industry Innovation Award
Read moreabout SYLKE® Receives the 2025 AAHKS Industry Innovation Award















